{"title":"A case of vaginal melanoma with multi-line immunotherapy and reflections","authors":"Xia Deng","doi":"10.5114/aoms/173154","DOIUrl":null,"url":null,"abstract":"A 69-year-old female patient was hospitalised for irregular vaginal bleeding for over 2 months and painful urination for over 1 month. An ultrasound examination in September 2019 revealed a vaginal mass. The vaginal wall biopsy pathology report dated 16 September 2019 (pathology No.: K1910569) showed malignant melanoma (MM). Immuno-histochemistry results were as follows: S-100 (+), HMB45 (+), MelanA (+), CK (−), Ki-67 (20–30%, +), SMA (−), CD4 (−), CD8 (−), CD68 (+) and PD-1 (−) (Figure","PeriodicalId":8278,"journal":{"name":"Archives of Medical Science","volume":"375 1","pages":"0"},"PeriodicalIF":3.0000,"publicationDate":"2023-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Medical Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5114/aoms/173154","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
A 69-year-old female patient was hospitalised for irregular vaginal bleeding for over 2 months and painful urination for over 1 month. An ultrasound examination in September 2019 revealed a vaginal mass. The vaginal wall biopsy pathology report dated 16 September 2019 (pathology No.: K1910569) showed malignant melanoma (MM). Immuno-histochemistry results were as follows: S-100 (+), HMB45 (+), MelanA (+), CK (−), Ki-67 (20–30%, +), SMA (−), CD4 (−), CD8 (−), CD68 (+) and PD-1 (−) (Figure
期刊介绍:
Archives of Medical Science (AMS) publishes high quality original articles and reviews of recognized scientists that deal with all scientific medicine. AMS opens the possibilities for young, capable scientists. The journal would like to give them a chance to have a publication following matter-of-fact, professional review by outstanding, famous medical scientists. Thanks to that they will have an opportunity to present their study results and/or receive useful advice about the mistakes they have made so far.
The second equally important aim is a presentation of review manuscripts of recognized scientists about the educational capacity, in order that young scientists, often at the beginning of their scientific carrier, could constantly deepen their medical knowledge and be up-to-date with current guidelines and trends in world-wide medicine. The fact that our educational articles are written by world-famous scientists determines their innovation and the highest quality.