The Reductive Synthesis of Silver Nanoparticles Using Sodium Citrate and Their Potential Medical Uses in Skin Diseases

Abstract

This study investigates how silver nanoparticles develop and how they might be used as an antibacterial agent to prevent and treat wound infections. The reduction procedure was used to create silver nanoparticles—sodium citrate functions as both a lowering and a stabilizing agent. The properties of the liquid silver nanoparticles were then examined using a UV-Vis Spectrometer, a Particle Size Analyzer (PSA), and a Transmission Electron Microscope (TEM). UV-Vis studies show that nanoparticles produced with 1% sodium citrate are the most stable. PSA and XRD analyses reveal that the smallest silver nanoparticles are approximately 8 nm, with an average size of approximately 30.2nm. According to TEM examination, silver nanoparticles with an FCC crystal structure. In studies, pathogenic microorganisms such as E. coli, Bacillus subtilis, and Staphylococcus aureus were employed to assess how successfully the washing process inhibited bacterial growth. The quantitative research demonstrates that increasing the soaking period to 36 hours kills all germs and results in a 100% reduction. The best time to soak wound therapy linen in synthetic silver nanoparticles was 36 hours.