Analytical Review on Escitalopram oxalate and their combinations in Bulk and Pharmaceutical Formulation

Abstract

As an antidepressant, escitalopram oxalate, a pure S-enantiomer derivative of citalopram, blocks selective serotonin reuptake. By preventing serotonin reuptake and boosting serotonin levels in synaptic clefts, this action exerts an antidepressant effect. The analytical method used to identify Escitalopram oxalate in pharmaceutical formulations, both alone and in combination with other antidepressants, was identified in this review. The simultaneous comparison and discussion of eighteen analytical techniques, including HPLC, HPTLC, stability-indicating strategies, UV spectroscopy, hyphenated techniques and bioanalytical procedures, is best demonstrated by this thorough analysis. Analytical development must be validated in order to produce reliable results for regulatory filings. The invention of drugs resulted in a revolution in human health.