Sinonasal adenocarcinoma: a case series

Abstract

Sinonasal malignancies are rare head and neck cancers. We present three patients with sinonasal adenocarcinomas that have different characteristics. The first patient was asymptomatic, and the nasoendoscopy revealed a nasopharyngeal mass. He was diagnosed with stage I papillary type adenocarcinoma and was treated with nasal endoscopic surgery, with no evidence of tumour recurrence for one year. In the second case, the patient had a unilateral nasal blockage with blood-stained nasal discharge. Nasoendoscopy showed a septal mass. The patient was diagnosed with stage II low-grade non-intestinal sinonasal adenocarcinoma (NITAC) and underwent two nasal endoscopic surgeries with no tumour recurrence after six months. In the third case, the patient reported ear fullness, blood-stained nasal discharges, and painless neck swelling. Nasoendoscopy showed a right septal mass, and he was diagnosed with stage IVc high-grade NITAC. He received concurrent chemoradiotherapy and is doing well three months after treatment completion.