Krukenberg tumour in a patient with secondary infertility – case report

IF 0.1 Q4 PEDIATRICS

Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine Pub Date : 2023-08-28 DOI:10.15557/pimr.2023.0024

Joanna Fechner, Anna Markowska

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引用次数: 0

Abstract

A patient with secondary infertility, diagnosed with an endometrial polyp and right ovarian cyst, was referred for hysterolaparoscopy treatment. The woman reported no symptoms. During the hospitalisation, in addition to the aforementioned issues, left ovarian lesions and ascites were identified. A 10 cm lesion in the right ovary exhibited abundant vascularity. Tumour markers (AFP, CEA, HE4, CA-125) and the ROMA algorithm were assessed and found to be within the normal range. Laparotomy revealed a high-grade malignant tumour of unknown origin confirmed by histological examination. Uterine resection with unchanged greater omentum was performed. Immunohistochemical tests revealed positive cytokeratin (CK) reaction, including CK7 and focal CK20, as well as a marker of proliferation Ki-67 in some cells (20–30%). Signet ring cells and positive mucicarmine stain reaction were detected. The histological evaluation confirmed a Krukenberg tumour originating most likely from the stomach. The patient was referred to the Maria Skłodowska-Curie Greater Poland Cancer for further treatment.

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继发性不孕症患者的Krukenberg肿瘤1例报告

一个继发性不孕症的病人，诊断为子宫内膜息肉和右卵巢囊肿，转介子宫腹腔镜治疗。这名妇女没有报告任何症状。在住院期间，除上述问题外，还发现左卵巢病变和腹水。右侧卵巢10cm病变显示血管丰富。评估肿瘤标志物(AFP, CEA, HE4, CA-125)和ROMA算法，发现在正常范围内。剖腹探查发现一不明来源的高级别恶性肿瘤，经组织学检查证实。行大网膜不变的子宫切除术。免疫组化检查显示细胞角蛋白(CK)反应阳性，包括CK7和局灶性CK20，以及一些细胞(20-30%)的增殖标志物Ki-67。印戒细胞和黏黏胺染色反应阳性。组织学检查证实为克鲁肯伯格瘤，极有可能起源于胃。患者被转介到Maria Skłodowska-Curie大波兰癌症中心接受进一步治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatria i Medycyna Rodzinna-Paediatrics and Family Medicine PEDIATRICS-

CiteScore

0.50

自引率

0.00%

发文量

审稿时长

20 weeks

期刊介绍： PEDIATRIA I MEDYCYNA RODZINNA is a peer-reviewed scientific journal publishing original articles that constitute significant contributions to the advancements of paediatrics and family medicine. In addition, PEDIATRIA I MEDYCYNA RODZINNA, publishes information from the medical associations, reports and materials from international congresses, letters to the Editor, information on new medical products as well as abstracts and discussions on papers published in other scientific journals, reviews of books and other publications.