A Rare Occurrence of Demyelinating Lesions of Bilateral Trigeminal Nerves: An Atypical Presentation of Pediatric Multiple Sclerosis

IF 0.2 Q4 PEDIATRICS
Elia Manfrini, Ludovica Falcioni, Vanna Cavassa, Eleonora Cocco, Stefano Sotgiu, Luca Saba
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引用次数: 0

Abstract

Abstract Pontine trigeminal root entry zone is a typical, although uncommon, location for multiple sclerosis (MS) lesions to occur. Here, we present a 17-year-old girl with nausea, vomiting, and vertigo. Neurological examination was consistent with central nystagmus, positive Romberg's test, and left-sided hyperreflexia. Baseline magnetic resonance imaging fulfilled McDonald 2017 criteria for MS and showed T2-hyperintense and T1-hypointense bilateral demyelinating lesions at the intramedullary portion of the trigeminal root of the fifth nerve, with no contrast enhancement or restricted diffusion. Bilateral intrapontine trigeminal involvement is a rare finding in MS, as well as the combined central and peripheral demyelination. Furthermore, very limited information and cases have been described in pediatric patients.
罕见的双侧三叉神经脱髓鞘病变:小儿多发性硬化症的非典型表现
摘要:脑桥三叉神经根进入区是多发性硬化症(MS)病变发生的典型部位,但并不常见。在这里,我们报告一位17岁的女孩,她有恶心、呕吐和眩晕。神经学检查符合中枢性眼球震颤,Romberg试验阳性,左侧反射亢进。基线磁共振成像符合McDonald 2017的MS标准,显示双侧第5神经三叉根髓内部t2高、t1低的脱髓鞘病变,无造影剂增强或弥散受限。双侧脑膜内三叉神经受累在多发性硬化症中是一个罕见的发现,以及合并中央和周围脱髓鞘。此外,在儿科患者中描述的信息和病例非常有限。
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来源期刊
CiteScore
0.40
自引率
0.00%
发文量
52
期刊介绍: The Journal of Pediatric Neurology is a multidisciplinary peer-reviewed medical journal publishing articles in the fields of childhood neurology, pediatric neurosurgery, pediatric neuroradiology, child psychiatry and pediatric neuroscience. The Journal of Pediatric Neurology, the official journal of the Society of Pediatric Science of the Yüzüncü Yil University in Turkiye, encourages submissions from authors throughout the world. The following articles will be considered for publication: editorials, original and review articles, rapid communications, case reports, neuroimage of the month, letters to the editor and book reviews.
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