Prevalence of Diabetes Mellitus Among Newly Detected Sputum Positive Pulmonary Tuberculosis Patients and Associated Risk Factors

Q3 Pharmacology, Toxicology and Pharmaceutics

Biomedical and Pharmacology Journal Pub Date : 2023-09-30 DOI:10.13005/bpj/2755

Rashmi Hullalli, M R Gudadinni, Rohith M

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Abstract

Background and Objectives: Tuberculosis (TB) and Diabetes Mellitus (DM) co-morbidity are of rising public health problems. There is growing evidence that DM is an important risk factor for TB. This study was carried out to know the prevalence of DM among newly detected sputum-positive pulmonary TB patients registered in the District Tuberculosis Centre and also to assess the risk factors of DM among TB patients. Methods: In a cross-sectional study newly detected sputum-positive pulmonary TB patients were screened for DM (those having symptoms of DM). Further, they were diagnosed by doing random blood glucose levels (≥200 mg/dl.). Mean, standard deviation (SD), Chi-square and Freeman-Halton Fisher exact test were used to know the significant association. p value less than 0.05 was considered statistically significant. Results: A total of 215 TB patients were included in the study. The prevalence of DM among TB patients was found to be 23.7% (2.8% known and 97.8% new cases). Significant associations were found between age (>46 years), educational status, smoking habits, alcohol consumption, physical activity, presence of symptoms of DM and family H/o DM. Interpretation and Conclusion:Routine screening for DM is mandatory because of the increasing prevalence which may help in early diagnosis and also reduce the complication by proper management which in turn helps in the successful outcome of TB treatment.

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新检痰阳性肺结核患者糖尿病患病率及相关危险因素分析

背景与目的:结核病(TB)和糖尿病(DM)的合并症是一个日益严重的公共卫生问题。越来越多的证据表明，糖尿病是结核病的一个重要危险因素。本研究旨在了解在区结核病中心登记的新检痰阳性肺结核患者中糖尿病的患病率，并评估结核病患者中糖尿病的危险因素。方法:在一项横断面研究中，对新发现的痰阳性肺结核患者(有糖尿病症状的患者)进行糖尿病筛查。此外，通过随机血糖水平(≥200mg /dl)进行诊断。采用均值、标准差(SD)、卡方检验和Freeman-Halton Fisher精确检验来了解显著相关性。P值小于0.05认为有统计学意义。结果:共纳入215例结核病患者。结核病患者中糖尿病患病率为23.7%(已知2.8%，新发病例97.8%)。年龄(46岁)、受教育程度、吸烟习惯、饮酒习惯、体力活动、糖尿病症状和家庭H/o型糖尿病之间存在显著关联。解释和结论:糖尿病的常规筛查是强制性的，因为患病率越来越高，这可能有助于早期诊断，并通过适当的管理减少并发症，从而有助于结核病治疗的成功结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biomedical and Pharmacology Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology

CiteScore

1.20

自引率

0.00%

发文量

189

期刊介绍： Biomedical and Pharmacology Journal (BPJ) is an International Peer Reviewed Research Journal in English language whose frequency is quarterly. The journal seeks to promote research, exchange of scientific information, consideration of regulatory mechanisms that affect drug development and utilization, and medical education. BPJ take much care in making your article published without much delay with your kind cooperation and support. Research papers, review articles, short communications, news are welcomed provided they demonstrate new findings of relevance to the field as a whole. All articles will be peer-reviewed and will find a place in Biomedical and Pharmacology Journal based on the merit and innovativeness of the research work. BPJ hopes that Researchers, Research scholars, Academician, Industrialists etc. would make use of this journal for the development of science and technology. Topics of interest include, but are not limited to: Biochemistry Genetics Microbiology and virology Molecular, cellular and cancer biology Neurosciences Pharmacology Drug Discovery Cardiovascular Pharmacology Neuropharmacology Molecular & Cellular Mechanisms Immunology & Inflammation Pharmacy.