SLC47 family of multidrug and toxin extrusion transporters in GtoPdb v.2023.1

Ken-ichi Inui
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Abstract

Human multidrug and toxin extrusion MATE1 and MATE2-K are H+/organic cation antiporters [1]. They are predominantly expressed in the kidney and play a role in renal tubular secretion of cationic drugs.
GtoPdb v.2023.1中多药和毒素挤出转运蛋白SLC47家族
人多药和毒素挤出MATE1和MATE2-K是H+/有机阳离子反转运蛋白[1]。它们主要在肾脏中表达,在肾小管分泌阳离子药物中起作用。
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