Assessment of Hematological Parameters in the Diagnosis Brucella Epididymorchitis: Comparison of Brucella Epididymorchitis and Non-Brucella Epididymorchitis

Dilek BULUT, Çağrı COŞKUN, Uğur AYDIN
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Abstract

Objective: To analyze the parameters that can facilitate the differential diagnosis of brucella epididymorchitis (BEO) and non-brucella epididymorchitis (NBEO) and to facilitate early diagnosis. Material And Methods: The data of 23 BEO patients and 80 NBEO patients, who applied in a tertiary center in eastern Turkey, where brucellosis is common, were retrospectively analyzed. Age, hemogram parameters (white blood cell (WBC)), neutrophil, lymphocyte, monocyte, eosinophil, basophil, platelet, neutrophil-to-lymphocyte ratio (NLR), monocyte-to-lymphocyte ratio (MLR), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), red blood cell distribution width (RDW), biochemical parameters (aspartate transaminase and alanine aminotransferase), inflammatory markers (C-reactive protein, erythrocyte sedimentation rate, and procalcitonin), urine culture, and scrotal doppler ultrasound findings were analyzed retrospectively and were compared between BEO and NBEO groups. Results: In the comparison of the BEO and NBEO groups, there was a significant difference between the two groups in WBC count, neutrophil count, monocytes count, NLR, MLR, MPV, and procalcitonin levels (p = 0.035, p = 0.007, p = 0.003, p = 0.005, p = 0.01, p < 0.001, p < 0.001, respectively). Conclusions: The NLR may be promising for use in the early diagnosis of BEO. The MPV also drew attention as parameters that can be evaluated
血液学参数在诊断布氏菌附睾炎中的评价:布氏菌附睾炎与非布氏菌附睾炎的比较
目的:探讨布鲁氏菌性附睾支气管炎(BEO)与非布鲁氏菌性附睾支气管炎(NBEO)的鉴别诊断参数,促进早期诊断。材料与方法:回顾性分析土耳其东部布鲁氏菌病高发地区某三级中心23例BEO患者和80例NBEO患者的资料。年龄、血象参数(白细胞(WBC)、中性粒细胞、淋巴细胞、单核细胞、嗜酸性粒细胞、嗜碱性粒细胞、血小板、中性粒细胞与淋巴细胞比值(NLR)、单核细胞与淋巴细胞比值(MLR)、血小板与淋巴细胞比值(PLR)、平均血小板体积(MPV)、红细胞分布宽度(RDW)、生化参数(天冬氨酸转氨酶和丙氨酸转氨酶)、炎症标志物(c反应蛋白、红细胞沉降率、降钙素原)、尿液培养、回顾性分析BEO组和NBEO组的阴囊多普勒超声表现。结果:BEO组与NBEO组比较,两组患者白细胞计数、中性粒细胞计数、单核细胞计数、NLR、MLR、MPV、降钙素原水平差异均有统计学意义(p = 0.035, p = 0.007, p = 0.003, p = 0.005, p = 0.01, p <0.001, p <分别为0.001)。结论:NLR在BEO的早期诊断中有较好的应用前景。MPV作为可评价的参数也备受关注
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