Analysis of stomach metastasis resulting from different cancers in a retrospective review

Abstract

Abstract Context and purpose Research reviews the findings, course of therapy, and outcomes of gastric metastases (GM). With this investigation, we hope to contribute to the increasing amount of information by providing practitioners with a reliable and practical platform for understanding stomach metastases from various primary malignancies. Methods : This study covered papers published in English from the MEDLINE and Cochrane databases until May 2022. The deleted materials included editorial emails, billboards, surgical photos, and non-English publications. Hematogenous and lymphogenic metastases were noted, yet primary tumor progression and dissemination were not. Using pre-established criteria for eligibility, the ultimate selection was made after the articles and abstracts were reviewed and cross-referenced. Results : A total of 186 GM cases were listed in 1,521 papers that were eventually found. The average of sixty-two years. The majority of GM cases (67) were attributed to reproductive cancers, with lung tumors (33 patients), carcinoma of the kidney (20 patients), and melanomas (19 patients) trailing closely behind. The main treatment strategy for metastases is excision surgery (n = 62), often in combination with immunotherapy or chemotherapy (ChT). Among the 78 therapeutic options, ChT was the second-most preferred choice. Furthermore, immunotherapy was one of the most preferred treatment alternatives (n = 10) following surgery and ChT. Conclusions : Heterogeneity was inevitable because 172 case reports from different journals were included in this systematic review. Certain papers have omitted crucial facts such as comprehensive monitoring and scientific information. Additionally, since every article featured was a personal study, it was not possible to evaluate the quality of the work. In the majority of the 172 cases that were examined, resected procedures occurred; on rare occasions, immunotherapy and ChT were also combined. The best course of action for patients with stomach metastases requires further investigation.