Serologic Monitoring of the Toxoplasmosis in Pregnant Women in Brazzaville, Congo

Fils Landry Mpelle, Sekangue Obili Jery, E. N. Ontsira Ngoyi, Etienne Nguibi, J. B. Mouankie, R. Moyen, S. Kobawila, Gabriel Ahombo
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Abstract

Objectives: The objective of this work was to determine the immune status by researching antitoxoplasmic IgG and IgM. Methods: this is a prospective study from November 4, 2013 to April 4, 2014 carried out at the Exau Kenn medical center laboratory located opposite the Makelekele Base Hospital (I Brazzaville district). A toxoplasmic serology was taken from all pregnant women (first trimester) admitted to the Laboratory as part of a medical follow-up of their pregnancies. Serodiagnosis was performed by the agglutination technique associated with the indirect solid phase immunoenzymatic technique (EIA). Results: Of 139 pregnant women included in our study, 56.12% were immunized and 43.88% unimmunized. The seroprevalence was 69.04%. The percentage of women aged under 20 was 22.22%; and those between 20 and 39 years old was 46.77%; then 31.01% among those over 39 years of age. The risk factors incriminated in toxoplasmic infection for our study were: contact with soil, consumption of raw vegetables, level of hygiene and contact with cats. Conclusion: toxoplasmosis in pregnant women in Brazzaville is a real problem that must be regularly revealed in order to put in place an action plan to identify and evade it.
刚果布拉柴维尔孕妇弓形虫病血清学监测
目的:通过研究抗弓形虫IgG和IgM来确定免疫状态。方法:这是一项2013年11月4日至2014年4月4日在位于Makelekele基地医院对面的Exau Kenn医学中心实验室进行的前瞻性研究(布拉柴维尔区)。作为妊娠医学随访的一部分,对所有进入实验室的孕妇(妊娠早期)进行了弓形虫血清学检查。血清诊断采用凝集技术联合间接固相免疫酶技术(EIA)。结果139例孕妇免疫接种率为56.12%,未免疫接种率为43.88%。血清阳性率为69.04%。20岁以下女性占22.22%;20 ~ 39岁占46.77%;39岁以上占31.01%。在我们的研究中,弓形虫感染的危险因素是:接触土壤、食用生蔬菜、卫生水平和与猫接触。结论:布拉柴维尔孕妇弓形虫病是一个真实存在的问题,必须定期披露,以便制定行动计划,以识别和避免它。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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