Oxidative Stress and Antioxidant Status in Immune Thrombocytopenia

Abstract

Immune thrombocytopenia (ITP) is an autoimmune disorder characterized by an isolated thrombocytopenia that may manifest as skin and mucous membrane bleeding. However, the pathogeny of this disease is much elusive. Increasing evidences demonstrate oxidative stress plays an essiential role in the pathogenesis of autoimmune diseases including ITP, which may provide a novel therapeutic approach.