Inhibitory Effect of Japanese Green Tea Extracts on Growth of Canine Oral Bacteria

E. Isogai, H. Isogai, N. Fujii, K. Kimura, H. Miura, M. Hayashi, S. Namioka, Masayoshi Kawasaki, Kunihiko Ikeda
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引用次数: 10

Abstract

The ethanol extracts from Japanese green tea from the leaf of Camellia sinensis (Japanese green tea) contained polyphenol compounds as major components. By liquid and gas chromatographic analysis, 5 catechin compounds were detected. The tea extracts (Deochon 13189-B, Deochon 30 EX and Camellia 50 EX) were found to effectively inhibit the growth of canine oral bacteria. Minimum inhibitory concentration (MIC) was different among genus, species and strains of the bacteria. Canine periodontal pathogens such as Porphyromonas assacharolytica were sensitive to the tea extracts. Similar result was obtained by using human oral bacteria including periodontal pathogens. These results suggest that the tea extracts would be useful as anti-periodontitis agent and/or flora control agent in dogs.
日本绿茶提取物对犬口腔细菌生长的抑制作用
日本绿茶茶叶乙醇提取物主要成分为多酚类化合物。通过液相和气相色谱分析,检测到5种儿茶素类化合物。茶提取物(Deochon 13189-B、Deochon 30ex和Camellia 50ex)能有效抑制犬口腔细菌的生长。细菌的最小抑菌浓度(MIC)在属、种、菌株之间存在差异。犬牙周病原菌如溶糖卟啉单胞菌对茶提取物敏感。用包括牙周病原体在内的人类口腔细菌也获得了类似的结果。这些结果表明,茶提取物可能是有效的抗牙周炎剂和/或菌群控制剂。
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