[Application possibilities of human bone-collagen substance as a transplant in skeletal surgery].

Abstract

We present first results of our clinical trial with a demineralized-bone-matrix (DBM) not only as a transplant to fill up a defect of bone but above all to induce local osteogenesis. Indications and practical applications of the material of transplants are described. By help of the clinical progresses and the reports of laboratory examinations the biological compatibility is regarded in this paper. Roentgen morphologically fine structures of the transplants and their transplant beds are described in serial roentgenography and used as evaluation of processes of transformation and building in of bones. The in a relative good time appearing markings of trajectories of the fine structures in the sphere of the transplant as a sign of accelerated regeneration of "organic bony substance" allows the expectation on being released osteogenetic potencies by DBM for the induction of local bone regeneration.