Time-frequency analysis based motion detection in perfusion weighted MRI

Abstract

In this paper, we present a novel automated method to detect motion in perfusion weighted images (PWI), which is a type of magnetic resonance imaging (MRI). In PWI, blood perfusion is measured by injecting an exogenous tracer called bolus into the blood flow of a patient and then tracking it in the brain. PWI requires a long data acquisition time to form a time series of volumes. Hence, motion occurs due to patient's unavoidable movements during a scan, which in turn results into motion corrupted data. There is a necessity of detection of these motion artifacts on captured data for correct disease diagnosis. In PWI, intensity profile gets disturbed due to occurrence of motion and/or bolus passage through the blood vessels. There is no way to distinguish between motion occurrence and bolus passage. In this paper, we propose an efficient time-frequency analysis based motion detection method. We show that proposed method is computationally inexpensive and fast. This method is evaluated on a DSC-MRI sequence with simulated motion of different degrees. We show that our approach detects motion in a few seconds.