Autoimmune thyroiditis in adolescents: Two different presentations

Abstract

Autoimmune thyroiditis is one of the most common causes of acquired hypothyroidism in children and adolescents. Both genetic susceptibility and environmental factors play a role in etiopathogenesis. We report two cases of autoimmune thyroiditis here with varied presentation. Both of them had different clinical features of hypothyroidism at presentation. On investigation, both of them had elevated thyroid-stimulating hormone (TSH), low T4 and elevated anti-Thyroid peroxidase (TPO) antibodies. Case 1 also had elevated anti-TG antibody level. Based on these findings, diagnosis of autoimmune thyroiditis was made and started on levothyroxine tablet, for which both of them showed both clinical and biochemical improvements.