The role of inflammation in the development of metabolic disorders in patients with arterial hypertension

L. Zhuravlyova, M. V. Kulikova
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引用次数: 5

Abstract

In recent years, the comorbid course of cardiovascular diseases, primarily arterial hypertension with impaired carbohydrate tolerance or type 2 diabetes mellitus, is becoming increasingly important in the developed countries of the world. In this regard, the need for a more detailed study of the general mechanisms of the development of arterial hypertension, pre-diabetes, and type 2 diabetes mellitus, namely inflammation, is increasing. There are many studies that investigate the role of inflammation in hypertension and associated glucometabolic disorders, but the exact mechanisms by which activated immune cells lead to the development and maintenance of these conditions remain to be seen. Obtaining new data in this area may contribute to a deeper understanding of cardiometabolic disorder pathogenesis. It may allow to predict the progression of these disorders at the early stages and to develop effective preventive and therapeutic tactics for their correction.
炎症在动脉高血压患者代谢紊乱发展中的作用
近年来,心血管疾病的共病过程,主要是动脉高血压与碳水化合物耐量受损或2型糖尿病,在世界发达国家变得越来越重要。在这方面,对动脉高血压、前驱糖尿病和2型糖尿病(即炎症)发展的一般机制进行更详细研究的需求正在增加。有许多研究调查了炎症在高血压和相关糖代谢紊乱中的作用,但激活免疫细胞导致这些疾病发展和维持的确切机制仍有待观察。在这一领域获得新的数据可能有助于更深入地了解心脏代谢紊乱的发病机制。它可以在早期阶段预测这些疾病的进展,并为其纠正制定有效的预防和治疗策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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