Sistemi di somministrazione insulinica automatizzata open source: a che punto siamo?

Il Diabete Pub Date : 2023-07-10 DOI:10.30682/ildia2302h
Daniela Bruttomesso, Federico Boscari
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Abstract

The artificial pancreas or automated insulin delivery (AID) system is an important step forward in the treatment of diabetes. Besides commercial AID systems, open-source automated insulin delivery systems (opensource-AID), known more colloquially as “Do-it-Yourself Artificial Pancreas Systems” (DIY APS) have become available. They couple algorithms developed by patients with diabetes, with commercially available and regulatory-approved insulin pumps and continuous glucose monitoring (CGM) sensors. These closed loop systems, are categorized by the technology and algorithm they incorporate (OpenAPS, Android APS or Loop). Until now only one open-source algorithm has been approved by Food and Drug Administration. Different studies, observational, real time and randomized-controlled have shown that AID open-source systems can improve metabolic control and quality of life in patients with diabetes, while decreasing the burden of diabetes management. Aim of this paper is to summarize data from the literature and to reason about the implications that the arrival of this new technique will have for patients and caregivers.
胰岛素自动开源管理系统:我们在哪里?
人工胰腺或自动胰岛素输送(AID)系统是糖尿病治疗的重要一步。除了商业辅助胰岛素输送系统,开源的自动胰岛素输送系统(开源-AID),更通俗的说法是“DIY人工胰腺系统”(DIY APS)已经可用。他们将糖尿病患者开发的算法与市售和监管批准的胰岛素泵和连续血糖监测(CGM)传感器相结合。这些闭环系统根据它们所采用的技术和算法(OpenAPS, Android APS或loop)进行分类。到目前为止,只有一种开源算法得到了食品和药物管理局的批准。不同的观察性、实时和随机对照研究表明,AID开源系统可以改善糖尿病患者的代谢控制和生活质量,同时减轻糖尿病管理的负担。本文的目的是从文献中总结数据,并对这种新技术的到来对患者和护理人员的影响进行推理。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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