{"title":"[Electrophoretic studies of the composition of peripheral mononuclear cells during operations with extracorporeal circulation].","authors":"J Rychly, D Oldag, A D Krüger","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>The increased incidence of infections after operations can be connected with changes of the immunocompetent cells. Mononuclear blood-cells were investigated by means of the cell electrophoresis during and after operations under the extracorporeal circulation, because electrophoretically different cells correlate with several immunological phenotypes. A heavy decrease of the electrophoretic quick mobility cell population was found out on the first postoperative day above all. This change allows itself the interpretation by decreasing the T-lymphocytes connected to a relative increase of monocytes, B-cells, and immature T-cells. Besides a lower quotient of the quick and low mobility T-cells refers to a lower immunoregulatory quotient CD4/CD8 after operation. Changes of the cell composition becomes evident also in dependence on the bypass length and the blood supply.</p>","PeriodicalId":77647,"journal":{"name":"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zeitschrift fur experimentelle Chirurgie, Transplantation, und kunstliche Organe : Organ der Sektion Experimentelle Chirurgie der Gesellschaft fur Chirurgie der DDR","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The increased incidence of infections after operations can be connected with changes of the immunocompetent cells. Mononuclear blood-cells were investigated by means of the cell electrophoresis during and after operations under the extracorporeal circulation, because electrophoretically different cells correlate with several immunological phenotypes. A heavy decrease of the electrophoretic quick mobility cell population was found out on the first postoperative day above all. This change allows itself the interpretation by decreasing the T-lymphocytes connected to a relative increase of monocytes, B-cells, and immature T-cells. Besides a lower quotient of the quick and low mobility T-cells refers to a lower immunoregulatory quotient CD4/CD8 after operation. Changes of the cell composition becomes evident also in dependence on the bypass length and the blood supply.
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