How genetic therapy can be used to treat patients undergoing clinical depression?

Abstract

Clinical depression can be described as a common medical disorder that negatively affects how an individual feels, thinks, and acts. Today, the chances of a person suffering from depression are much more common worldwide, and it is critical to understand depression and most importantly how to treat the disease. While it currently remains unclear exactly how depression works in the human body, research shows that a protein called P11 might play a vital role in the molecular and cellular mechanisms underlying depression in the body. According to research, as the level of P11 protein decreases, it increases an individual’s risk of undergoing depression. The main problem is that the existing treatment, which includes medication and psychotherapy, is not as effective as it could be for treating such a disease. Genetic therapy treatment would be an attractive alternative treatment for depression treatment since regulating the levels and mechanisms involving protein P11 would hopefully alleviate one’s symptoms of depression in the body. This paper intends to highlight the benefits of using gene therapy to treat depression and elaborate on why the treatment may be useful.