Frequency of Vitamin D Deficiency and its Association with CP Class in Cases of Liver Cirrhosis

Pakistan Journal of Medical & Health Sciences Pub Date : 2022-09-30 DOI:10.53350/pjmhs22169993

Zoha Nasir, Muhammad Usaid Khan, Hina Batool, N. Nayyer, J. Iqbal, M. Zubair

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Abstract

Objective: To find out the frequency of vitamin D deficiency and its association with CP class in cases of liver cirrhosis. Study Design: Cross sectional study. Place and Duration: Bahawal Victoria Hospital, Bahawalpur (From September 2021 to March 2022). Methodology: Total 195 cirrhotic patients of any etiology, 20-40 years of age both male and female were selected. Vitamin D deficiency and its association with CP class was assessed. Results: Mean age of cirrhotic patients was 38.46 ± 11.383 years. Out of 195 patients, vitamin D was deficient in 83 (43%) patients. Vitamin D deficiency was found in CP class A, B and C 7 (7.78%) patients, 13 (44.83%) patients and 63 (82.89%) patients respectively. CP class had significant (P = 0.000) association with vitamin D deficiency. Conclusion: In this study, higher proportion of cirrhotic patients had deficient levels of vitamin D. Most of the patients were between 20-40 years. A higher number of male patients had deficient levels of vitamin D. It is also concluded that vitamin D deficiency is significantly associated with CP class. Keywords: liver cirrhosis, CP class, vitamin D, hepatic osteodystrophy

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肝硬化患者维生素D缺乏频率及其与CP分级的关系

目的:了解肝硬化患者维生素D缺乏的频率及其与CP分级的关系。研究设计:横断面研究。地点和时间:巴哈瓦尔布尔巴哈瓦尔维多利亚医院(2021年9月至2022年3月)。方法:选取195例肝硬化患者，年龄20-40岁，男女不限。评估了维生素D缺乏及其与CP等级的关系。结果:肝硬化患者平均年龄为38.46±11.383岁。在195名患者中，83名(43%)患者缺乏维生素D。CP A、B、C类患者维生素D缺乏症分别为7例(7.78%)、13例(44.83%)和63例(82.89%)。CP等级与维生素D缺乏显著相关(P = 0.000)。结论:在本研究中，肝硬化患者中维生素d缺乏的比例较高，大多数患者年龄在20-40岁之间。男性患者维生素D缺乏的比例较高，维生素D缺乏与CP类型有显著关系。关键词:肝硬化，CP级，维生素D，肝性骨营养不良

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Pakistan Journal of Medical & Health Sciences

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