Shwachman-Diamond Syndrome

Abstract

symptoms may vary between individuals. The primary features of SDS include: bone marrow dysfunction (leading to inadequate production of some types of blood cells), pancreatic defects (leading to difficulties in digesting food), skeletal abnormalities, and short stature. Other secondary features may affect some but not all people affected with SDS. People with SDS are at risk for serious, sometimes fatal, complications such as severe infections, bone marrow failure and acute myelogenous leukemia. SHWACHMAN-DIAMOND SYNDROME