Environmental Enrichment and Neuronal Plasticity

G. Clemenson, F. Gage, C. Stark
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引用次数: 17

Abstract

This chapter reviews the literature on environmental enrichment and specifically discusses its influence on the hippocampus of the brain. In animal models, the term “environmental enrichment” is used to describe a well-defined manipulation in which animals are exposed to a larger and more stimulating environment. This experience has been shown to have a powerful and positive impact on hippocampal cognition and neuroplasticity in animals. In humans, however, the translation of environmental enrichment is less clear. Despite the fact that humans live considerably more enriching lives compared to laboratory animals, studies have shown that training and expertise (such as exercise and spatial exploration) can lead to both functional and structural changes in the human brain. This chapter is a comprehensive review of environmental enrichment, drawing parallels between animal models and humans to present a more complete understanding of environmental enrichment.
环境富集与神经元可塑性
本章回顾了有关环境富集的文献,并着重讨论了环境富集对大脑海马区的影响。在动物模型中,术语“环境富集”用于描述一种定义明确的操作,即动物暴露于更大、更刺激的环境中。这种经历已被证明对动物海马认知和神经可塑性有强大而积极的影响。然而,在人类中,环境富集的转化就不那么清楚了。尽管与实验动物相比,人类的生活要丰富得多,但研究表明,训练和专业知识(如锻炼和空间探索)可以导致人类大脑的功能和结构变化。本章是对环境富集的全面回顾,在动物模型和人类之间画出相似之处,以呈现对环境富集的更完整的理解。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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