Liquid reagent storage in self-pumping lab-on-a-chip systems for quick assay and biosensor integration

Abstract

We present a novel approach for liquid reagent storage in lab-on-a-chip systems. A special normally-closed valving technology using thermal-release adhesive tapes is presented. The cartridge and experimental setup is explained. The thermal release tape is opened by attaching heating elements to the areas to be opened. Heating parameters were optimized and a newly developed cartridge containing nine liquid reservoirs is emptied completely automatically, including valve-opening steps and integrated pumping.