The Trojan Effect: Would prevention of air pollution be a better solution to Alzheimer’s disease than developing medication?

Abstract

Emerging evidence is showing that air pollution is a chronic source of neuroinflammation, which has a causal relationship with Alzheimer ’s disease (AD), an increasingly common and devastating illness in elderly populations. A report on the association between PM from air pollution and AD provided scientific explanations for the mechanisms driving air pollution-induced CNS pathology, which stimulates calls for action at the political level. This scoping review considers the range of recognised and novel approaches associated with AD, highlighting how neurobiology, sociology of medicine and eco-politics collaborate to generate the interdisciplinary picture of the effects of PM on this malignancy. Such holistic approaches will allow this field to move forward and could lead to an improvement of actionable policies.