Role of metabolic surgery in remission of type 2 diabetes mellitus in patients with obesity

V. S. Mozgunova, G. V. Semikova, A. Volkova, E. N. Ostroukhova, B. G. Lukichev
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Abstract

Type 2 diabetes mellitus and obesity are two socially significant diseases, the prevalence of which has now assumed pandemic proportions. Obesity, as a rule, precedes the development of type 2 diabetes, being the most powerful risk factor for the development of this disease. In patients with obesity and type 2 diabetes with a BMI >35 kg/m2, bariatric surgery is recommended if glycemic control cannot be achieved after several attempts at non-surgical treatment of obesity. There is no doubt the effectiveness of bariatric surgery not only in the treatment of obesity, but also in achieving remission of type 2 diabetes. It seems relevant to study the predictors of achieving remission of type 2 diabetes, as well as factors that can worsen the prognosis. The purpose of the review: to study the effectiveness of metabolic surgery in achieving remission of type 2 DM, as well as predictors of remission of type 2 DM in obese patients after bariatric surgery.
代谢手术在肥胖患者2型糖尿病缓解中的作用
2型糖尿病和肥胖症是两种具有社会意义的疾病,其发病率现已达到流行病的程度。肥胖通常先于2型糖尿病的发展,是2型糖尿病发展的最强大的风险因素。对于BMI为35 kg/m2的肥胖和2型糖尿病患者,如果多次尝试非手术治疗肥胖仍不能控制血糖,则建议进行减肥手术。毫无疑问,减肥手术不仅在治疗肥胖方面有效,而且在实现2型糖尿病的缓解方面也有效。这似乎与研究2型糖尿病缓解的预测因素以及可能使预后恶化的因素有关。本综述的目的是:研究代谢手术在实现2型糖尿病缓解方面的有效性,以及肥胖患者减肥手术后2型糖尿病缓解的预测因素。
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