Bladder cancer cell imaging system

M. Weilguni, W. Smetana, M. Edetsberger, G. Kohler
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Abstract

A system for observing bladder cancer cells in form of a miniaturized fluorescence microscope has been developed. Attention has turned to integrate this system in an existing LTCC (Low Temperature Cofired Ceramics) module. Software with a region detecting algorithm has been written to automatically detect the captured images. The cancer specimen was marked with hypericin, which is selective on bladder cancer cells. After coloring the specimen was excited with green light of a high power LED. The red emitting hypericin marked cells were captured by a CMOS chip and evaluated with the software to confirm or negate a suspicion of cancer.
膀胱癌细胞成像系统
研制了一种小型荧光显微镜观察膀胱癌细胞的系统。注意力已经转向将该系统集成到现有的LTCC(低温共烧陶瓷)模块中。编写了具有区域检测算法的软件,用于自动检测捕获的图像。肿瘤标本用金丝桃素标记,金丝桃素对膀胱癌细胞有选择性。上色后,用大功率LED的绿光激发试样。发射红色金丝桃素标记的细胞被CMOS芯片捕获,并用软件进行评估,以确认或否定癌症的怀疑。
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