The Indirect Implication of SARS-CoV-2 Resulting in Kayexalate Toxicity in a Patient with Acute Kidney Injury

C. Middleton, W. Daley, N. Varshney
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Abstract

The clinical features of corona virus disease 2019 (COVID-19) are variable, but the majority of patients experience mild flu-like symptoms. The cases of severe disease include complications such as progressive pneumonia, acute kidney injury, multi-organ failure, and even death. This paper explores the association between COVID-19 and its effect on multiple organ systems and how the subsequent treatment of this disease can itself lead to morbidity and mortality. We present a case which emphasizes the life threatening gastrointestinal complications associated with treatment of acute kidney injury (AKI) in a patient with COVID-19. We conclude that the patients whose treatment regimens utilize medical resins should be closely monitored for gastrointestinal complications so as to mitigate the known adverse effects associated with these drugs, such as colonic mucosal ulceration, perforation, or even death.
SARS-CoV-2导致急性肾损伤患者Kayexalate毒性的间接意义
2019冠状病毒病(COVID-19)的临床特征是可变的,但大多数患者会出现轻微的流感样症状。重症病例包括进行性肺炎、急性肾损伤、多器官衰竭甚至死亡等并发症。本文探讨了COVID-19与其对多器官系统的影响之间的关联,以及这种疾病的后续治疗如何导致发病率和死亡率。我们报告了一个病例,强调了与COVID-19患者急性肾损伤(AKI)治疗相关的危及生命的胃肠道并发症。我们的结论是,使用医用树脂治疗方案的患者应密切监测胃肠道并发症,以减轻与这些药物相关的已知不良反应,如结肠黏膜溃疡,穿孔,甚至死亡。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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