Allografts in Periodontal Regeneration

Abstract

Bone allografts are being widely used in field of periodontology, many of clinicians are unfamiliar with their preparation and processing as well as their use as safe and effective graft materials. The major issues associated with these materials are antigenicity and risk of disease transmission from donor to recipient. To minimize the risk, the production of an allograft and its distribution and implantation requires strict attention to detail through a comprehensive process. With an increasing requirement in clinical practice for bone grafting procedures, there is an increase in patient’s demands for assurance that bank bone will not be infected with pathogens. To ensure the patients, surgeons should be able to cite factual information and recommendations by responsible organizations regarding safety of allografts. Knowledge of human bone allograft procurement, processing, and tracking may allow dentists to better educate patients and address concerns about this valuable treatment option. The purpose of this review is to update about the procurement, safety and efficacy of allografts.