Retroperitoneal Malignant Peripheral Nerve Sheath Tumour Associated with Vertebral Involvement and Spinal Cord Compression

Abstract

Malignant peripheral nerve sheath tumour (MPNST) is usually seen in soft tissue. Intraosseous MPNST is rare, and so is secondary extension. Skeletal involvement usually involves the mandible and other long bones. Vertebral involvement is usually metastatic in nature. Here we report a case of a large retroperitoneal MPNST involving the L1 vertebra and producing spinal cord compression in a patient with neurofibromatosis (NF).