{"title":"Lewy Body Disease","authors":"Vaibhav Walia, M. Garg","doi":"10.4018/978-1-5225-5282-6.CH014","DOIUrl":null,"url":null,"abstract":"Fritz Heinrich Lewy described the intracytoplasmic inclusions found in the neurons for the very first time. In 1919 these inclusions were termed as “LBs” by Tretiakoff. LBs were found in the brain of the patients suffering from Lewy body disease (LBD). LBD is characterized by the presence of Parkinsonian symptoms in the earlier stages and dementia in the later stages of the disease. LBs were classified on the basis of the region of the brain in which they are distributed and so is the case of the LBD means the type of the LBD depends on the anatomical areas of the brain involved. LBD is not a single disorder. It is a spectrum of disorders. This chapter addresses the entire profile of LBs, types, composition, formation, and various LB pathologies as well as diagnostic criteria and pharmacotherapy.","PeriodicalId":230045,"journal":{"name":"Research Anthology on Diagnosing and Treating Neurocognitive Disorders","volume":"14 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Research Anthology on Diagnosing and Treating Neurocognitive Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4018/978-1-5225-5282-6.CH014","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Fritz Heinrich Lewy described the intracytoplasmic inclusions found in the neurons for the very first time. In 1919 these inclusions were termed as “LBs” by Tretiakoff. LBs were found in the brain of the patients suffering from Lewy body disease (LBD). LBD is characterized by the presence of Parkinsonian symptoms in the earlier stages and dementia in the later stages of the disease. LBs were classified on the basis of the region of the brain in which they are distributed and so is the case of the LBD means the type of the LBD depends on the anatomical areas of the brain involved. LBD is not a single disorder. It is a spectrum of disorders. This chapter addresses the entire profile of LBs, types, composition, formation, and various LB pathologies as well as diagnostic criteria and pharmacotherapy.
Fritz Heinrich Lewy首次描述了在神经元中发现的胞浆内包涵体。1919年,这些内含物被Tretiakoff称为“lb”。在路易体病(LBD)患者的大脑中发现了lb。LBD的特点是在疾病的早期阶段出现帕金森症状,在疾病的晚期出现痴呆。LBs是根据它们所分布的大脑区域来分类的,LBD的情况也是如此,这意味着LBD的类型取决于所涉及的大脑解剖区域。LBD不是一种单一的疾病。这是一系列的疾病。本章讨论了LB的整个概况,类型,组成,形成,各种LB病理以及诊断标准和药物治疗。