Perfusion Imaging

Abstract

What is Perfusion • Perfusion describes the amount of blood delivered to the capillary beds of a block of tissue in a certain time period. • Transport of oxygen, glucose and other nutrients from blood to tissue. • Occurs at the capillary level (radius ~ 5 μm) • It is typically characterized by three quantities: cerebral blood volume (CBV), cerebral blood flow (CBF), and mean transit time (MTT). The typical imaging voxel contains several thousand capillaries. • CBF and MTT measurements necessarily rely on techniques sensitive to motion (for instance, bolus tracking techniques), CBV may be measured with other methods (for instance, in a steady state).