{"title":"Hipercalcemia como urgencia médica","authors":"J.A. Nuevo-González","doi":"10.1016/S1132-8460(09)73229-5","DOIUrl":null,"url":null,"abstract":"<div><p>La hipercalcemia es una alteración del metabolismo del calcio que, producida bruscamente o por encima de 14,5<!--> <!-->mg/dl, puede provocar complicaciones sistémicas que comprometan la vida del paciente. Es una urgencia médica que se presenta con mayor frecuencia en la enfermedad tumoral avanzada, generalmente a través de la activación de la proteína relacionada con la hormona paratiroidea. Se debe iniciar un tratamiento inmediato, siendo la sueroterapia intensiva y los bifosfonatos intravenosos las claves para conseguir una restauración metabólica rápida. Zolendronato se considera actualmente el bifosfonato más eficaz para la hipercalcemia aguda.</p></div><div><p>Hypercalcemia is a metabolic disorder of calcium that may cause systemic complications when is produced suddenly or above 14.5<!--> <!-->mg/dl. It is considered as a medical emergency that appears more frequently at advanced malignant disease, usually through the activation of parathyroid hormone-related protein. It should be treated promptly and an intensive therapy with fluids and intravenous bisphosphonates are the keys to achieve metabolic restoration. At present, zoledronic acid is considered the most effective bisphosphonate for acute hypercalcemia.</p></div>","PeriodicalId":101109,"journal":{"name":"Revista Espa?ola de Enfermedades Metabólicas óseas","volume":"18 3","pages":"Pages 51-55"},"PeriodicalIF":0.0000,"publicationDate":"2009-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S1132-8460(09)73229-5","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Espa?ola de Enfermedades Metabólicas óseas","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1132846009732295","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
La hipercalcemia es una alteración del metabolismo del calcio que, producida bruscamente o por encima de 14,5 mg/dl, puede provocar complicaciones sistémicas que comprometan la vida del paciente. Es una urgencia médica que se presenta con mayor frecuencia en la enfermedad tumoral avanzada, generalmente a través de la activación de la proteína relacionada con la hormona paratiroidea. Se debe iniciar un tratamiento inmediato, siendo la sueroterapia intensiva y los bifosfonatos intravenosos las claves para conseguir una restauración metabólica rápida. Zolendronato se considera actualmente el bifosfonato más eficaz para la hipercalcemia aguda.
Hypercalcemia is a metabolic disorder of calcium that may cause systemic complications when is produced suddenly or above 14.5 mg/dl. It is considered as a medical emergency that appears more frequently at advanced malignant disease, usually through the activation of parathyroid hormone-related protein. It should be treated promptly and an intensive therapy with fluids and intravenous bisphosphonates are the keys to achieve metabolic restoration. At present, zoledronic acid is considered the most effective bisphosphonate for acute hypercalcemia.
高钙血症是一种钙代谢紊乱，如果突然发生或超过14.5 mg/dl，可导致危及患者生命的全身并发症。它是一种医学紧急情况，最常出现在晚期肿瘤疾病中，通常通过激活甲状旁腺激素相关蛋白。应立即开始治疗，强化血清治疗和静脉注射双膦酸盐是实现快速代谢恢复的关键。佐仑膦酸盐目前被认为是治疗急性高钙血症最有效的双膦酸盐。Hypercalcemia是metabolic到处of calcium,可能引起的系统必须when is生产的突然或在复审mg / dl。它被认为是一种医疗紧急情况，在晚期肿瘤疾病中更常见，通常通过激活甲状甲醛激素相关蛋白。It should be对一名and an intensive治疗with fluids and ivpi bisphosphonates are the keys to的metabolic restoration。= =地理= =根据美国人口普查，这个县的面积为。
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
