Importance of vitamin d level in early-stage chronic lymphocytic leukemia and its comparison with healthy population

Abstract

Chronic lymphocytic leukemia (CLL) is a chronic lymphoproliferative hematological malignancy accompanied by a monoclonal proliferation of mature B lymphocytes. CLL is the most common type of adult leukemia with 5/100,000 incidence rate every year in Western countries (1-3). CLL is a disease that mostly affects elder; 80% of the patients are aged more than 50 years (4,5). However, CLL has a heterogeneous course according to the clinical and molecular characteristics (6,7).