Microbiome-associated medicine: How are the world of microbes and the world of people connected?

Abstract

Over the past two decades, the microbial community of an organism – the microbiota – has been recognized as a fundamental factor determining human physiology and pathology. The microbiome is a variable system that not only adapts to signals and information coming from humans, but also affects its host. A promising area of clinical medicine is the prediction of changes in the microbiome of athletes, in people with various diseases, after the use of medicines, including antibacterial, surgical interventions, which will lead to an understanding of ways and methods of their correction. Fundamentally new and innovative technologies are being developed to create pharmacologically active components based on the microbiome of healthy people, which can later be used to maintain and restore the stability and functioning of the human ecosystem.