Dynamics of Human-Beta-Defensin-1 Level as a Marker of the Anti-Tuberculosis Treatment Effectiveness and Treatment Adherence

Abstract

Available prognostic markers for tuberculosis like sputum conversion and X-ray dynamics are not always sensitive enough. They give results delayed in time and sputum analysis is not always available, as some patients do not cough out sputum. That is why, the study of prognostic markers of the tuberculosis course is becoming an urgent trend in phthisiology. Human-beta-defensin-l can be one of them. This work showed the possibility of use of dynamics of Human-bet a-defens in-l as a marker of anti-tuberculosis treatment effectiveness and treatment adherence.