Mechanical characterization of floating cell using whole chip deformation mechanism

Abstract

We present a method of cell mechanical characterization using a robot integrated microfluidic chip (robochip). The robochip has a microchannel, a force sensor and an on-chip probe. On-chip probe is actuated by whole chip deformation mechanism. Firstly, we designed the robochip. Secondary, we fabricated the robochip. Finally, we measured the young's modulus of zona pellucida by using Hertz contact theory.