Processing and Simulation of Output from Lab-on-a-Chip Devices in Cell Mechanical Analysis

Abstract

in this paper we present algorithms and methods used to implement the processing of an image output from lab-an-a-chip devices. Such microdevices are used in the analysis of single biological cells, their characterization and study of their behaviour under different conditions. We mention algorithms of cell detecting, characterization based on their image and automatic distinguishing and tracking in lab-on-a-chips for analysis of sinzle cells. The paper is also devoted to the mechanical simulation of cell deformation under pressure. The model of a light transmittance through deflected cell geometry is presented.