Balanoposthitis in clinical practice: evaluation of the effectiveness of the Balanex complex.

Abstract

Introduction. Despite the frequent occurrence of balanoposthitis, due to the wide variety of pathogens, it is often difficult to find an effective therapy. Purpose. To evaluate the extent of changes in complaints during therapy by the complex drug Balanex and its effectiveness. Materials and methods. The study was conducted as a prospective comparative cohort. The study included 120 patients with typical complaints for balanoposthitis. Patients were randomized according to chronic diseases and balanoposthitis therapy. The first group included 59 men with nonspecific balanoposthitis, for whom Balanex cream gel was prescribed topically 2 times a day as a therapy. The study observation group consisted of 32 men with balanoposthitis on the background of diabetes mellitus, for whom therapy Balanex cream gel was prescribed topically 2 times a day. The control group included 29 men with nonspecific balanoposthitis, for whom therapy by a combined cream (antibacterial + antifungal component) was used topically 2 times a day. Results and discussion. In all patients, the results of repeated microbiological examination were negative. The time of disappearance of the patient's disturbing symptoms ranged from 2 to 7 days, on average it was 3.2 ± 1.1 days, the median value was 3 days. At the same time, the presence of diabetes mellitus in the patient significantly prolonged the period of disappearance of symptoms to 3.9 days. The average value of this indicator was 3.0±0.6 vs. 3.9±1.6 vs. 3.0±0.8 days (p<0,001). Conclusions. Balanex cream gel significantly and comparably with the combined cream reduces the severity of symptoms that occur with balanoposthitis, including patients with diabetes mellitus.