Holoprosencephaly In A Nigerian Cadaver: An Original Case Report

Abstract

Forebrain abnormalities include cases of abnormally large or small brain volume (Megaloencephally and Microencephaly), abnormally formed gyri (agyria and polymicrogyria), abnormal migration of neurons (neuronal heterotopias), incomplete separation of the cerebral hemispheres (Holoprosencephaly) and agenesis of the corpus callosum. During a routine dissection of formalin-fixed cadavers in our Gross laboratory, a partial fusion of the cerebral hemispheres in the precentral cortex was encountered in a male adult cadaver. The falx cerebri was incomplete with crescentic inferior margin overlying the fused part. Agyri and abnormally formed gyri were also noticed.