Perbedaan Kadar D-Dimer Plasma pada Penderita Kanker Ginekologi Disertai Covid-19 dan Tanpa Covid-19 di RSUP Dr. M. Djamil Padang

Abstract

Knowledge of coagulopathy in cancer and COVID-19 is important to be understood by clinicians on duty, especially in referral hospitals in order to do appropriate monitoring and management according to the patient's condition and prevent morbidity and mortality in cancer patients who also suffer from COVID-19. Objective: to determine the difference in plasma D-dimer levels in patients with gynaecological cancer with COVID-19 and without COVID-19 who were treated at RSUP Dr. M. Djamil Padang. Methods: the study used an analytical research design with a retrospective cohort approach. The Mann Whitney U test was performed because the assumption of normality was not met. The analysis used was univariate and bivariate Chi Square analysis. Results: gynaecological cancer patients who are confirmed positive for COVID-19 mostly (79.2%) have abnormal plasma D Dimer levels (>500 gr/dL), gynaecological cancer patients who are not confirmed positive for COVID-19 mostly (84.9%) have abnormal plasma D Dimer levels (>500 gr/dL), Mann Whitney test on differences in plasma D-Dimer levels in gynaecological cancer patients with COVID-19 and without COVID-19 can be concluded that: there is no difference in plasma D-Dimer levels in patients with gynaecological cancer accompanied by COVID-19 and without COVID-19, Chi Square test can be concluded: there is no relationship between plasma D-Dimer levels in patients with gynaecological cancer accompanied by COVID-19 (p=0.447).