The Effectiveness of Autologous Platelet-Rich Plasma PRP In the Therapy of Infertile Women with Poor Ovarian Reserve POR, A Retrospective Chart-Review Study

Abstract

Platelet-rich plasma (PRP), also known as autologous platelet gel, is “autologous blood with concentrations of platelets above baseline levels, which contains at least seven growth factors”. plasma rich in growth factors (PRGF), and platelet concentrate (PC), is a high concentration of autologous platelets suspended in a small volume of plasma after centrifugation [1]. More than 800 types of protein molecules, cytokines, hormones, and chemo-attractants are carried by the platelets [2]. When platelets get activated, numerous biologically active proteins that stimulate cell proliferation, growth, and differentiation are released. Activated platelets also release various types of growth factors like platelet-derived growth factor (PDGF), transforming growth factor β (TGF-β), fibroblast growth factor (FGF), epidermal growth factor (EGF), insulin-like growth factor (IGF-1), and hepatocyte growth factor (HGF) [3] Table 1.