Study of the Effect of Micro patterning on Apatite Formation in Osteoblasts

Abstract

Copyright: © 2013 Meng Y. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Collaborators at Stony Brook University (Stony Brook, New York, USA) and New York Institute of Technology (Old Westbury, New York, USA) recently conducted a research project to investigate bone mineralization on artificially patterned biomaterials. This project aimed to seek out novel ways to enhance the osteogenic capability of osteoblasts by culturing them on substrates containing various micro topographies. This was the first study that combines micro patterning and synchrotron techniques to examine in-situ apatite production of cultured cells in response to altered surface dimension.