{"title":"Oncological aspects of the biological action of low-level laser radiation: II. Investigation of primary mechanisms and clinical applications","authors":"A. Ivanov, S. Zakharov","doi":"10.1117/12.375252","DOIUrl":null,"url":null,"abstract":"The second part of this paper presents the results of many years of research on the primary stages of the biological mechanism of LLLR action. The scanning electron microscopy method revealed some activation of the cell membrane in the irradiated human lymphocytes. This is shown in ultrastructure surface change. In the study on magnetic characteristics paramagnetic properties were fond at 633 nm irradiation of cell suspension, connected wit the formation of free-radical products as a result of primary photochemical processes. In order to identify the primary photoacceptor that sets off a chain of biochemical, structural and metabolic changes in the cell, biological action spectra were studied. With the laser cytodiffractometer coincidence between the action spectra and the absorption band of molecular oxygen was established.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"131 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1999-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Research on Laser Use in Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.375252","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 3
Abstract
The second part of this paper presents the results of many years of research on the primary stages of the biological mechanism of LLLR action. The scanning electron microscopy method revealed some activation of the cell membrane in the irradiated human lymphocytes. This is shown in ultrastructure surface change. In the study on magnetic characteristics paramagnetic properties were fond at 633 nm irradiation of cell suspension, connected wit the formation of free-radical products as a result of primary photochemical processes. In order to identify the primary photoacceptor that sets off a chain of biochemical, structural and metabolic changes in the cell, biological action spectra were studied. With the laser cytodiffractometer coincidence between the action spectra and the absorption band of molecular oxygen was established.