Tình hình nhiễm COVID-19 và tiêm chủng vắc xin trên địa bàn tỉnh Khánh Hòa

Abstract

Background: Covid-19 pandemic continues its complicated situation although vaccination campaign has been accelerated. There are still Covid-19 infections among those who have been vaccinated with various Covid-19 vắc xins. Objective: The study aims to examine the association between Covid-19 infection and vaccination status among people who contracted with Covid-19 in Khanh Hoa province in the second half of the year 2021 through comparison of (1) virus load based on Ct index; (2) length of stay in the health facilities; and (3) days of conversion to negative results of PCR test. Comparison of these three indices between AstraZeneca vắc xin and Verocell vắc xin was also made. Methods: Case series design was applied to recruit confirmed cases of Covid-19 infection. Non-parametric analysis was used to compare medians of variables of Ct values, length of hospitalization (by days), and days of negative conversion of PCR tests. Analysis was performed with R software. Results: Ct value median among people who have vaccinated fully was lower than those who haven’t vaccinated yet. The length of hospitalization among people who have been vaccinated or fully vaccinated were longer than those who haven’t vaccinated yet (13 and 14 days compared with 11 days). There was a need of 11 days for negative conversion of PCR test among Covid-19 cases who haven’t vaccinated yet, shorter than Covid-19 cases who have vaccinated (12 days). These three indices were better in people who vaccinated with AstraZeneca vắc xin compared with Verocell vắc xin. Conclusions: Among confirmed cases of Covid-19 infection, Ct median of people who haven’t vaccinated yet was higher than others. Shorter length of hospitalization was observed among people who haven’t vaccinated yet, and longer days of negative conversion of PCR test was reported in vaccinated people. There was primary superior evidence of AstraZeneca vắc xin compared with Verocell vắc xin.