Risk of COVID-19 in Healthcare Workers of the Nephrology Department in a Tertiary Hospital

Quiroga Borja, G. Martin, R. Muñoz, Zurita Nelly Daniela, Villagrasa José Ramón, M. Cristina, S. Paloma, B. Guillermina
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Abstract

Introduction and Aim: The COVID-19 pandemic has caused devastating socio-sanitary effects worldwide pointing in healthcare workers. The aim of the present study was to analyze COVID-19 incidence, clinical presentation and treatment in the nephrologist of a tertiary hospital. Material and Methods: All healthcare workers of the Nephrology Department were included. All of them were tested for SARS-CoV-2 virus by real-time reverse transcription-polymerase chain reaction (rRT-PCR) and for antibodies against this virus (IgG and IgM). Data were collected about symptoms, chest X-ray, prescribed treatments and exposure time. All the variables were compared between COVID-19 infected and non-infected workers. Results: Thirty workers were included, of which 13 (43%) had COVID-19 infection. Participation in Emergency on-call shifts was associated to COVID-19 (p = 0.02). Among the COVID-19 patients, 7 developed symptoms; the most frequent was fever followed by myalgia. Three patients received hydroxycloroquine, one corticosteroids and 6 azithromycin. The use of azithromycin was associated to fever (p = 0.01), dysgeusia (p = 0.03), asthenia (p = 0.008) and cough (p = 0.03). Prescription of hydroxycloroquine was associated to dysgeusia (p < 0.001) and cough (p = 0.04). Positive rRT-PCR and IgG was associated to participation in on-call shifts. Conclusions: The prevalence of COVID-19 in the Nephrology Department is high and associated to the performance of on-call shifts.
某三级医院肾内科医护人员COVID-19感染风险分析
导言和目的:2019冠状病毒病大流行在全球范围内对卫生保健工作者造成了毁灭性的社会卫生影响。本研究的目的是分析某三级医院肾病科的COVID-19发病率、临床表现和治疗情况。材料与方法:纳入肾内科所有医护人员。采用实时逆转录-聚合酶链反应(rRT-PCR)对所有人进行SARS-CoV-2病毒检测和该病毒抗体(IgG和IgM)检测。收集了有关症状、胸部x光片、处方治疗和暴露时间的数据。对感染和未感染的工作人员进行所有变量的比较。结果:共纳入工作人员30人,其中13人(43%)感染新冠肺炎。参与紧急值班与COVID-19相关(p = 0.02)。新冠肺炎患者中出现症状7例;最常见的症状是发烧,其次是肌痛。3例患者接受羟氯喹治疗,1例皮质类固醇治疗,6例阿奇霉素治疗。阿奇霉素的使用与发热(p = 0.01)、吞咽困难(p = 0.03)、乏力(p = 0.008)和咳嗽(p = 0.03)相关。羟氯喹处方与吞咽困难(p < 0.001)和咳嗽(p = 0.04)相关。rRT-PCR和IgG阳性与参与值班班次相关。结论:肾脏病科的COVID-19患病率较高,且与值班表现有关。
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