Evaluation of the relationships between ER, PR, c-erbB2, Ki67, E-Cadherin expressions, Nottingham histological grade and some clinical parameters in breast carcinomas

Mürüvvet Akçay Çelik, Yeliz Kaşko Arıcı
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Abstract

To Aim: In this study, it was aimed to evaluate the relationships between Estrogen (ER), Progesterone (PR), c-erbB2, Ki67, E-Cadherin expressions, Nottingham histological grade and some clinical parameters in breast carcinomas. Material and Methods: A total of 74 patients diagnosed with breast carcinoma in our pathology department between 2018-2019 were included in this study. Immunohistochemical preparations stained with ER, PR, c-erbB2, Ki67, E-Cadherin were evaluated and analyzed retrospectively. For ER and PR, ≥1% expression was considered positive staining, and
乳腺癌中ER、PR、c-erbB2、Ki67、E-Cadherin表达与诺丁汉组织学分级及部分临床参数的关系
目的:本研究旨在探讨乳腺癌中雌激素(ER)、孕激素(PR)、c-erbB2、Ki67、E-Cadherin表达与诺丁汉组织学分级及一些临床参数的关系。材料与方法:本研究共纳入我院病理科2018-2019年诊断为乳腺癌的74例患者。对ER、PR、c-erbB2、Ki67、E-Cadherin染色的免疫组化制剂进行回顾性评价和分析。ER和PR≥1%表达为阳性染色
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