Radioiodine therapy in differentiated thyroid cancer

A. Isah, Sofiullah Abubakar, G. Yunusa, Z. Jawa, J. Momodu
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Abstract

Well differentiated thyroid cancers are slow-growing tumors with low disease-specific mortality rates for locoregional disease. Diagnosis is through histopathology of symptomatic or incidentally detected thyroid nodules. The management depends on the tumor stage and risk stratification. Monitoring, surgery, radioactive iodine, radiotherapy and targeted therapy play various role in management depending on stage and risk of recurrence. Radioactive iodine is a form of iodine which is unstable and emits both gamma (γ) rays and beta (β) rays. This enables its usage in both diagnosis and therapy for well differentiated thyroid cancers that retain the physiological process of concentrating iodine. This review article highlights, in summary, the role of radioiodine in the management of well differentiated thyroid cancers and also helps create awareness among physicians in Nigeria.
放射性碘治疗分化型甲状腺癌
分化良好的甲状腺癌是一种生长缓慢的肿瘤,在局部疾病中具有较低的疾病特异性死亡率。诊断是通过组织病理学的症状或偶然发现甲状腺结节。治疗取决于肿瘤分期和风险分层。监测、手术、放射性碘、放疗和靶向治疗在治疗中发挥着不同的作用,这取决于复发的分期和风险。放射性碘是碘的一种形式,它不稳定,同时发出γ射线和β射线。这使得它能够用于诊断和治疗分化良好的甲状腺癌,保留了浓缩碘的生理过程。总之,这篇综述文章强调了放射性碘在治疗分化良好的甲状腺癌中的作用,并有助于提高尼日利亚医生的认识。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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