Pathology of Rhino-orbito-cerebral Mucor Mycosis

Abstract

Mucormycosis is a life-threatening infection that occurs in patients who are immunocompromised because of impair host defences which permit growth and dissemination of fungus. The risk factors for invasive disease are uncontrolled diabetes mellitus with ketoacidosis; malignancies (haematological and solid organ); hematopoietic stem cell transplantation (HSTC); solid organ transplantation; high dose corticosteroids/immuno-suppression; deferoxamine therapy, malnutrition, neonatal prematurity etc. Immunocompetent individuals gets infected when there is a breach in body defence mechanism. Like skin injuries, burns, contaminated bandages. (1)