Progress in the Application of Targeted Agents in Non-small Cell Cancer

Abstract

Research subject: primary targeted preparation, that is, the drug is released from the capillary bed into the target site; Secondary targeted preparation, that is, drug release from special cells (such as tumor cells) entering the target; Tertiary targeted preparations are drugs that act on certain parts of cells. Research methods: Compared with traditional preparations, targeted preparations can improve drug selectivity, reduce adverse reactions, enhance efficacy and improve patient compliance, and become the focus of new drug research and development. Therefore, scientific and reasonable targeted evaluation techniques and methods should be established based on this point to improve the safety, effectiveness and quality control of such drug preparations. Objective: This paper reviews the targeted application of anti-tumor targeting agents, and introduces the targeted technology and application from the aspects of targeting and pharmacology, so as to provide reference for the development trend of anti-tumor targeting agents in the future. Conclusion: According to the study, attention should be paid to improving the drug encapsulation rate and drug loading, and increasing the drug stability, so as to obtain drug preparations with large drug loading, good stability and strong targeting.